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Hypothyroidism is a common autoimmune disorder that affects nearly 12% of the United States population, predominantly women and people over age 65

Hypothyroidism affects 1 in 300 people in the United States
Women are 5 to 9 times more likely than men to have hypothyroidism
More than 70% of patients with hypothyroidism have Hashimoto’s Thyroiditis
The prevalence of hypothyroidism grew from 9.6% of the population in 2012 to 13.95% in 2023

Hypothyroidism is more common than you might think. In the United States alone, nearly 12% of the population, or about 40 million people, are living with this endocrine disorder. It’s likely that you know someone – a friend, a family member, or a colleague – who is managing hypothyroidism. While this condition can lead to various health complications if left untreated, it can be effectively managed with the right treatment plan and regular follow-ups with a healthcare team. With proper care, individuals with hypothyroidism can lead healthy, normal lives.

What is Hypothyroidism?

Hypothyroidism, also known as an underactive thyroid, is a condition where the thyroid gland does not produce enough thyroid hormones. This gland, located at the front of the neck, is responsible for the body’s metabolism (the way it uses energy) and major functions such as heart rate.

The symptoms of hypothyroidism depend on the severity of the hormone deficiency. These symptoms tend to develop slowly, often over several years. At first, you may barely notice the symptoms of hypothyroidism, such as fatigue and weight gain. But as your metabolism continues to slow, you may develop more-obvious problems. Hypothyroidism symptoms may include tiredness, increased sensitivity to cold, constipation, dry skin, weight gain, puffy face, hoarse voice, coarse hair and skin, muscle weakness, muscle aches, tenderness and stiffness, menstrual cycles that are heavier than usual or irregular, thinning hair, slowed heart rate (also called bradycardia), depression, and memory problems.

The most common cause of hypothyroidism is when your immune system starts to attack itself, making antibodies against the thyroid gland. Other causes include autoimmune diseases, such as Hashimoto’s thyroiditis, surgical removal of the thyroid, and radiation treatment.

Diagnosis for Hypothyroidism is usually based on blood levels of thyroid-stimulating hormone (TSH) and free thyroxine (T4). If TSH is high and T4 is low, then the diagnosis is hypothyroidism.

While Hypothyroidism can lead to various health complications if left untreated, it can be effectively managed with the right treatment plan.

Hypothyroidism Symptoms

Do you suspect or know that you have Hypothyroidism? You may experience symptoms such as these:

  • Tiredness.
  • More sensitivity to cold.
  • Constipation.
  • Dry skin.
  • Weight gain.
  • Puffy face.
  • Hoarse voice.
  • Coarse hair and skin.
  • Muscle weakness.
  • Muscle aches, tenderness and stiffness.
  • Menstrual cycles that are heavier than usual or irregular.
  • Thinning hair.
  • Slowed heart rate, also called bradycardia.
  • Depression.
  • Memory problems.

Traditional Treatments for Hypothyroidism

The standard treatment for hypothyroidism is taking daily thyroid hormone replacement medication. The most commonly prescribed medication is synthetic levothyroxine, which is identical to the T4 hormone that the thyroid naturally makes. There are also other types of thyroid hormone replacement medications, such as liothyronine (T3) and natural desiccated thyroid (T4 and T3).

Levothyroxine

Levothyroxine works by replacing the thyroid hormone that your thyroid gland is not making enough of. You’ll likely start to feel better one or two weeks after you begin treatment. Treatment with levothyroxine is usually lifelong. Because the dosage you need may change, your healthcare provider may check your TSH level every year.

Dosage and Monitoring

Finding the right dosage of levothyroxine is crucial. Your healthcare provider checks your level of TSH about 6 to 8 weeks after you start taking the medicine. You may need another blood test to check TSH again six months later. Too much levothyroxine can cause side effects, such as tiredness, increased appetite, sleep problems, shakiness, and heart palpitations.

Other Medications

If levothyroxine alone doesn’t work or causes side effects, your doctor might add liothyronine. In some cases, natural desiccated thyroid hormones, which contain both T4 and T3, may be used.

Natural Remedies

In addition to traditional treatments, some natural remedies may help manage hypothyroidism. These include a selenium-rich, sugar-free, or gluten-free diet, as well as taking vitamin B supplements and probiotics. Always consult with a healthcare provider before starting any new treatment regimen.

Finding the Root Cause

Hypothyroidism is a condition that results from decreased production of thyroid hormones. The root causes of hypothyroidism can be varied and complex, but here are some of the most common ones:

  • Autoimmune Diseases: The most common cause of hypothyroidism is an autoimmune disease called Hashimoto’s disease. Autoimmune diseases occur when the immune system mistakenly attacks the body’s own cells. In the case of Hashimoto’s disease, the immune system targets the thyroid gland, affecting its ability to produce hormones.
  • Age and Gender: Increasing age and being female are risk factors for hypothyroidism. Women are more likely than men to develop hypothyroidism, and the risk increases with age.
  • Treatment for Hyperthyroidism: People who have been treated for hyperthyroidism (an overactive thyroid) are at risk of eventually developing hypothyroidism.
  • Thyroid Surgery: Having part or all of your thyroid gland removed can result in hypothyroidism.
  • Radiation Therapy: Radiation used to treat cancers of the head and neck can affect your thyroid gland and may lead to hypothyroidism.
  • Certain Medications: Some medicines can interfere with thyroid hormone production and lead to hypothyroidism.
  • Congenital Factors: Some people are born with a defective thyroid gland or no thyroid gland at all.
  • Pituitary Disorder: Less commonly, hypothyroidism can result from a disorder of the pituitary gland, which is located at the base of your brain and regulates the production of thyroid hormone.
  • Pregnancy: Some women may develop hypothyroidism during or after pregnancy.
  • Iodine Deficiency: In some parts of the world, iodine deficiency is a common cause of hypothyroidism.

 

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